Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7457488 | 0.98 | LOXL2 (0.58) | LOXL2KDM4EALDH1A1GAAHPGD | |
| Iodide SCHEMBL1343657 | 0.98 | LOXL2 (0.58) | LOXL2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL2237676 | 0.89 | LOXL2 (0.56) | LOXL2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL30665033 | 0.89 | LOXL2 (0.56) | LOXL2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL2364501 | 0.87 | LOXL2 (0.55) | LOXL2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL6114797 | 0.86 | CYP19A1 (0.54) | LOXL2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL6115140 | 0.85 | LOXL2 (0.53) | LOXL2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL10585446 | 0.85 | LOXL2 (0.53) | LOXL2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL6114811 | 0.85 | LOXL2 (0.53) | LOXL2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL6114551 | 0.85 | LOXL2 (0.53) | LOXL2KDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704113-B1 | BRIDGED BICYCLIC COMPOUNDS AS FARNESOID X RECEPTOR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-10-11 | — | — | EP | claimed |
| CN-109651379-A | One kind is containing pentaaza and/or the bicyclic diene ketone compounds of oxo dithia and its microwave solvent process for thermosynthesizing and application | 中南民族大学 | 2019-04-19 | — | — | CN | claimed |
| EP-1300134-B1 | Agent for dyeing keratinous fibres with isophthalaldehydes | HENKEL KGAA (DE) | 2006-04-26 | — | — | EP | claimed |
| CN-113117734-B | Zeolite catalyst and process for producing lower olefin | 三菱化学株式会社 | 2024-05-17 | — | — | CN | disclosed |
| US-11766667-B2 | Zeolite catalyst and method for producing lower olefin | MITSUBISHI CHEMICAL CORPORATION (JP) | 2023-09-26 | — | — | US | disclosed |
| CN-115785136-A | Boron-containing organic compound and application thereof | 深圳市华星光电半导体显示技术有限公司 | 2023-03-14 | — | — | CN | disclosed |
| US-20220211883-A1 | FAP-ACTIVATED RADIOTHERANOSTICS AND USES RELATED THERETO | TRUSTEES OF TUFTS COLLEGE | 2022-07-07 | — | — | US | disclosed |
| US-11180474-B2 | Dimethoxyphenyl substituted indole compounds as TLR7, TLR8 or TLR9 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-11-23 | — | — | US | disclosed |
| CN-113117734-A | Zeolite catalyst and process for producing lower olefin | 三菱化学株式会社 | 2021-07-16 | — | — | CN | disclosed |
| US-20210213433-A1 | ZEOLITE CATALYST AND METHOD FOR PRODUCING LOWER OLEFIN | MITSUBISHI CHEMICAL CORPORATION (JP) | 2021-07-15 | — | — | US | disclosed |
| CN-108290144-B | Zeolite catalyst and process for producing lower olefin | 三菱化学株式会社 | 2021-04-02 | — | — | CN | disclosed |
| EP-0975602-A4 | IMIDAZOLE AND IMIDAZOLINE DERIVATIVES AND USES THEREOF | GRUENENTHAL GMBH (DE) | 2003-01-22 | — | — | EP | disclosed |
| US-6485890-B2 | AQUEOUS DEVELOPER SOLUBLE POLYMER, SUCH AS A PHENOLIC RESIN; A COMPOUND THAT REDUCES THE AQUEOUS DEVELOPER SOLUBILITY OF THE POLYMER SUCH AS QUATERNIZED NITROGEN ATOM, SUCH AS QUINOLINIUM COMPOUNDS AND BENZOTHIAZOLIUM COMPOUNDS | KODAK POLYCHROME GRAPHICS, LLC | 2002-11-26 | — | — | US | disclosed |
| EP-0854879-B1 | NOVEL 5-O-DEOSAMINYL 6-O-METHYL ERYTHRONOLIDE A DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR PREPARING BIOLOGICALLY ACTIVE MATERIALS | AVENTIS PHARMA SA (FR) | 2002-01-16 | — | — | EP | disclosed |
| US-6280899-B1 | Relation to lithographic printing forms | KODAK POLYCHROME GRAPHICS, LLC | 2001-08-28 | — | — | US | disclosed |
| EP-0975602-A1 | IMIDAZOLE AND IMIDAZOLINE DERIVATIVES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2000-02-02 | — | — | EP | disclosed |
| US-6011142-A | ANTIBIOTICS | HOECHST MARION ROUSSEL (FR) | 2000-01-04 | — | — | US | disclosed |
| WO-1998046572-A1 | IMIDAZOLE AND IMIDAZOLINE DERIVATIVES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1998-10-22 | — | — | WO | disclosed |
| EP-0854879-A2 | NOVEL 5-O-DEOSAMINYL 6-O-METHYL ERYTHRONOLIDE A DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR PREPARING BIOLOGICALLY ACTIVE MATERIALS | HOECHST MARION ROUSSEL (FR) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997013774-A2 | NOVEL 5-O-DEOSAMINYL 6-O-METHYL ERYTHRONOLIDE A DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR PREPARING BIOLOGICALLY ACTIVE MATERIALS | HOECHST MARION ROUSSEL (FR) | 1997-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220211883-A1 | FAP-ACTIVATED RADIOTHERANOSTICS AND USES RELATED THERETO | FAP, FIBP, FGFR1 | LOXL2 1021/4885KDM4E 2796/4885ALDH1A1 789/4885 |
| US-11180474-B2 | Dimethoxyphenyl substituted indole compounds as TLR7, TLR8 or TLR9 inhibitors | TLR9, TLR7, TLR8 | LOXL2 3149/4885KDM4E 717/4885ALDH1A1 3767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.