Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 11/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9279907 | 1.00 | ALDH1A1 (0.44) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8907991 | 1.00 | ALDH1A1 (0.44) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8907217 | 0.91 | ALDH1A1 (0.57) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8908739 | 0.91 | ALDH1A1 (0.57) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8906822 | 0.89 | ALDH1A1 (0.46) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL9404265 | 0.85 | ALDH1A1 (0.53) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8909878 | 0.85 | ALDH1A1 (0.53) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL9097511 | 0.84 | ALDH1A1 (0.49) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL9099190 | 0.84 | ALDH1A1 (0.49) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8907044 | 0.83 | ALDH1A1 (0.55) | ALDH1A1LMNATP53MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683989-A | TREATMENT OF CARDIOVASCULAR AND NERVOUS SYSTEM DISORDERS | NOVO NORDISK A/S (DK) | 1997-11-04 | — | — | US | disclosed |
| US-5484774-A | 2, N6 -disubstituted adenosines, tri-O-ester derivatives and their pharmaceutical compositions to treat ischemias | NOVO NORDISK A/S (DK) | 1996-01-16 | — | — | US | disclosed |