Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NT5E | P21589 | 10/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909878 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8909939 | 0.89 | ALDH1A1 (0.48) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8327419 | 0.87 | ALDH1A1 (0.53) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8906822 | 0.86 | ALDH1A1 (0.46) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8907991 | 0.85 | ALDH1A1 (0.44) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL9279907 | 0.85 | ALDH1A1 (0.44) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8908736 | 0.85 | ALDH1A1 (0.44) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL23436497 | 0.85 | LMNA (0.69) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8818839 | 0.85 | LMNA (0.69) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL15679138 | 0.85 | LMNA (0.69) | ALDH1A1LMNATP53MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | disclosed |