Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 10/20 | 0.45 |
| ▸ | CA1 | P00915 | 8/20 | 0.45 |
| ▸ | CA12 | O43570 | 6/20 | 0.45 |
| ▸ | CA9 | Q16790 | 5/20 | 0.45 |
| ▸ | CA5A | P35218 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908775 | 1.00 | PRMT5 (0.46) | PRMT5WDR77CA2CA1CA12 | |
| SCHEMBL16052639 | 0.86 | PRMT5 (0.46) | PRMT5WDR77CA2CA1ALDH1A1 | |
| SCHEMBL10477956 | 0.86 | PRMT5 (0.46) | PRMT5WDR77CA2CA1ALDH1A1 | |
| SCHEMBL10477957 | 0.86 | PRMT5 (0.46) | PRMT5WDR77CA2CA1ALDH1A1 | |
| SCHEMBL7526079 | 0.79 | CA2 (0.53) | CA2CA1CA12CA9CA5A | |
| SCHEMBL4795645 | 0.78 | CA2 (0.39) | CA2CA1CA12CA9CA5A | |
| SCHEMBL2021778 | 0.77 | PRMT5 (0.48) | PRMT5WDR77ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL2021776 | 0.77 | PRMT5 (0.48) | PRMT5WDR77ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL1548227 | 0.75 | CA2 (0.46) | CA2CA1CA12CA9CA5A | |
| SCHEMBL2967503 | 0.75 | ALDH1A1 (0.50) | PRMT5WDR77ALDH1A1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612339-A | BACTERICIDES OR ANTISEPTICS | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1997-03-18 | — | — | US | disclosed |
| WO-1996022087-A1 | SULFONAMIDE-BASED COMPOSITIONS AND METHODS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-07-25 | — | — | WO | disclosed |
| WO-1996022097-A1 | NOVEL 2-HYDROXY-3-AMINOPROPYLSULFONAMIDES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-07-25 | — | — | WO | disclosed |
| US-5519060-A | ENZYME INHIBITORS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-05-21 | — | — | US | disclosed |