Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 5/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909187 | 0.85 | KMT2A (0.38) | CA2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL909752 | 0.85 | KMT2A (0.38) | CA2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL537494 | 0.85 | KMT2A (0.38) | CA2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL27388777 | 0.82 | KMT2A (0.36) | CA2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL3812470 | 0.79 | MEN1 (0.34) | CA2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL3809686 | 0.79 | MEN1 (0.34) | CA2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8908775 | 0.78 | PRMT5 (0.46) | CA2CA12CA1CA9MEN1 | |
| SCHEMBL8908779 | 0.78 | PRMT5 (0.46) | CA2CA12CA1CA9MEN1 | |
| SCHEMBL27283206 | 0.78 | CTSB (0.46) | CA2CA12CA1CA9PTGES2 | |
| SCHEMBL5153705 | 0.77 | ALDH1A1 (0.33) | CA2KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312404-A1 | Novel diepoxides and epoxy resins | PEWS R GARTH | 2008-12-18 | — | — | US | disclosed |
| US-7462728-B2 | Diepoxide derivatives of N,N*-disubstituted disulfonamides | PEWS R GARTH | 2008-12-09 | — | — | US | disclosed |
| US-20060128978-A1 | Diepoxide derivatives of N, N*-disubstituted disulfonamides | PEWS R G | 2006-06-15 | — | — | US | disclosed |