Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909174 | 1.00 | MET (0.48) | METSTAT3MAPTNPSR1ALDH1A1 | |
| SCHEMBL30970390 | 0.83 | ESR1 (0.46) | MAPTALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL27273810 | 0.83 | ESR1 (0.46) | MAPTALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL12004153 | 0.81 | MAPT (0.55) | METMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL1613587 | 0.81 | MAPT (0.55) | METMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL1613586 | 0.81 | MAPT (0.55) | METMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL9150112 | 0.81 | ALDH1A1 (0.43) | MAPTALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL9150118 | 0.81 | ALDH1A1 (0.43) | MAPTALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL14078326 | 0.81 | ALDH1A1 (0.47) | METMAPTNPSR1ALDH1A1KDM4E | |
| SCHEMBL18163764 | 0.80 | CNKSR1 (0.57) | STAT3MAPTNPSR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670664-A | Photosensitive organic compounds that release carbon monoxide upon illumination | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 1997-09-23 | — | — | US | disclosed |