Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 2/20 | 0.32 |
| ▸ | CTSH | P09668 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910229 | 1.00 | CTSK (0.34) | CTSKMETAP2METAP1ALOX5CTSL | |
| SCHEMBL8910237 | 1.00 | CTSK (0.34) | CTSKMETAP2METAP1ALOX5CTSL | |
| SCHEMBL9556641 | 0.82 | CTSK (0.40) | CTSKCTSLCTSBRENCTSH | |
| SCHEMBL9219308 | 0.82 | EPHX1 (0.39) | CTSKMETAP2METAP1ALOX5CTSL | |
| SCHEMBL9556645 | 0.82 | CTSK (0.40) | CTSKCTSLCTSBRENCTSH | |
| SCHEMBL9219298 | 0.82 | EPHX1 (0.39) | CTSKMETAP2METAP1ALOX5CTSL | |
| SCHEMBL9224171 | 0.82 | CTSK (0.40) | CTSKCTSLCTSBRENCTSH | |
| SCHEMBL9224178 | 0.82 | CTSK (0.40) | CTSKCTSLCTSBRENCTSH | |
| SCHEMBL9226123 | 0.79 | CTSK (0.35) | CTSKMETAP2CTSLCTSBREN | |
| SCHEMBL9226116 | 0.79 | CTSK (0.35) | CTSKMETAP2CTSLCTSBREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688946-A | DIPEPTIDES FOR HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | HOFFMANN LA ROCHE INC. (US) | 1997-11-18 | — | — | US | disclosed |