Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909210 | 0.82 | P2RX1 (0.54) | P2RX1REN | |
| SCHEMBL8908885 | 0.77 | REN (0.42) | REN | |
| SCHEMBL9800614 | 0.76 | P2RX1 (0.68) | P2RX1REN | |
| SCHEMBL9800618 | 0.76 | P2RX1 (0.68) | P2RX1REN | |
| SCHEMBL9800550 | 0.76 | P2RX1 (0.62) | P2RX1REN | |
| SCHEMBL8909057 | 0.76 | P2RX1 (0.62) | P2RX1REN | |
| SCHEMBL8909221 | 0.70 | P2RX1 (0.45) | P2RX1REN | |
| SCHEMBL9219298 | 0.68 | EPHX1 (0.39) | — | |
| SCHEMBL9219308 | 0.68 | EPHX1 (0.39) | — | |
| SCHEMBL9800480 | 0.67 | P2RX1 (0.42) | P2RX1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688946-A | DIPEPTIDES FOR HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | HOFFMANN LA ROCHE INC. (US) | 1997-11-18 | — | — | US | disclosed |