Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 5/20 | 0.42 |
| ▸ | CTSK | P43235 | 6/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CTSH | P09668 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908872 | 0.78 | REN (0.44) | RENCTSKCTSSTSHRCTSL | |
| SCHEMBL8909234 | 0.77 | P2RX1 (0.50) | REN | |
| SCHEMBL9219308 | 0.74 | EPHX1 (0.39) | CTSKCPB2CTSLCTSBEPHX1 | |
| SCHEMBL9219298 | 0.74 | EPHX1 (0.39) | CTSKCPB2CTSLCTSBEPHX1 | |
| SCHEMBL9256057 | 0.71 | REN (0.56) | RENTSHR | |
| SCHEMBL8909805 | 0.71 | REN (0.56) | RENTSHR | |
| SCHEMBL7276949 | 0.71 | REN (0.56) | RENTSHR | |
| SCHEMBL9800557 | 0.70 | REN (0.61) | RENCPB2 | |
| SCHEMBL8908881 | 0.69 | REN (0.41) | RENCTSKCTSSEPHX1 | |
| SCHEMBL9106410 | 0.67 | CTSK (0.65) | RENCTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688946-A | DIPEPTIDES FOR HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | HOFFMANN LA ROCHE INC. (US) | 1997-11-18 | — | — | US | disclosed |