Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.50 |
| ▸ | F2 | P00734 | 5/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442914 | 0.89 | F10 (0.52) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8908070 | 0.89 | F10 (0.57) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8907806 | 0.83 | F10 (0.50) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8604900 | 0.82 | F10 (0.53) | F10F2 | |
| SCHEMBL8442698 | 0.81 | F10 (0.49) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8442920 | 0.79 | F10 (0.57) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8441612 | 0.78 | CCR2 (0.49) | — | |
| SCHEMBL8439296 | 0.76 | F10 (0.52) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8441533 | 0.76 | F10 (0.64) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7364511 | 0.75 | F10 (0.57) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612363-A | FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1997-03-18 | — | — | US | disclosed |