Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 6/20 | 0.32 |
| ▸ | POLG | P54098 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907876 | 0.82 | CHRNB2 (0.38) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL8901161 | 0.79 | ALB (0.45) | ALBEP300POLG | |
| SCHEMBL8908488 | 0.78 | LMNA (0.43) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL3680116 | 0.72 | FGFR1 (0.52) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL23343373 | 0.72 | FGFR1 (0.44) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL10834771 | 0.70 | LMNA (0.44) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL12261276 | 0.70 | FGFR1 (0.47) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL236000 | 0.69 | FGFR1 (0.51) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL9837037 | 0.68 | FGFR1 (0.48) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL6379845 | 0.67 | FGFR1 (0.43) | LMNAPDE3ACACNA1FALBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997034891-A1 | SUBSTITUTED 1,3-THIAZOLIDINES AND 1,3-THIAZOLIDIN-4-ONES, METHOD FOR PREPARING SAME, AND USE THEREOF AS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-09-25 | — | — | WO | claimed |
| WO-1997034891-A1 | SUBSTITUTED 1,3-THIAZOLIDINES AND 1,3-THIAZOLIDIN-4-ONES, METHOD FOR PREPARING SAME, AND USE THEREOF AS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-09-25 | — | — | WO | disclosed |