Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALB | P02768 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | POLG | P54098 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891878 | 0.84 | DCK (0.37) | CHRNB2CHRNA4CHRNA5CHRNA7ALB | |
| SCHEMBL8909572 | 0.83 | CHRNB2 (0.36) | CHRNB2CHRNA4CHRNA5CHRNA7CACNA1F | |
| SCHEMBL8909430 | 0.82 | LMNA (0.43) | CACNA1FLMNAALBMAPTCACNA1D | |
| SCHEMBL8908293 | 0.77 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNA5CHRNA7MAPT | |
| SCHEMBL10569326 | 0.75 | PPM1B (0.44) | CHRNB2CHRNA4CHRNA5CHRNA7CACNA1F | |
| SCHEMBL9396763 | 0.73 | ALDH1A1 (0.36) | CHRNB2CHRNA4CHRNA5CHRNA7CACNA1F | |
| SCHEMBL6450341 | 0.70 | ALB (0.67) | CACNA1FLMNAALBMAPTCACNA1D | |
| SCHEMBL7932120 | 0.70 | ALB (0.67) | CACNA1FLMNAALBMAPTCACNA1D | |
| SCHEMBL9195454 | 0.70 | ALB (0.67) | CACNA1FLMNAALBMAPTCACNA1D | |
| SCHEMBL6448105 | 0.70 | ALB (0.67) | CACNA1FLMNAALBMAPTCACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997034891-A1 | SUBSTITUTED 1,3-THIAZOLIDINES AND 1,3-THIAZOLIDIN-4-ONES, METHOD FOR PREPARING SAME, AND USE THEREOF AS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-09-25 | — | — | WO | claimed |
| WO-1997034891-A1 | SUBSTITUTED 1,3-THIAZOLIDINES AND 1,3-THIAZOLIDIN-4-ONES, METHOD FOR PREPARING SAME, AND USE THEREOF AS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-09-25 | — | — | WO | disclosed |