Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6791759 | 0.86 | OPRD1 (0.53) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6247380 | 0.75 | LPAR1 (0.56) | OPRD1OPRM1 | |
| SCHEMBL2048377 | 0.74 | HSP90AA1 (0.52) | OPRD1OPRM1 | |
| SCHEMBL2042054 | 0.74 | USP2 (0.43) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6797137 | 0.73 | ALDH1A1 (0.54) | OPRD1OPRM1 | |
| SCHEMBL251637 | 0.73 | OPRD1 (0.50) | OPRD1OPRM1OPRK1 | |
| SCHEMBL252533 | 0.73 | OPRD1 (0.53) | OPRD1OPRM1OPRK1 | |
| SCHEMBL2047556 | 0.73 | USP2 (0.42) | OPRD1OPRM1OPRK1 | |
| SCHEMBL2052119 | 0.72 | OPRD1 (0.46) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6796380 | 0.70 | OPRM1 (0.53) | OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023466-A1 | NOVEL COMPOUNDS WITH ANALGESIC EFFECT | ASTRA PHARMA INC. (CA) | 1997-07-03 | — | — | WO | claimed |