Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.34 |
| ▸ | DHFR | P00374 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584885 | 0.84 | TSHR (0.50) | SMN1; SMN2CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL14806869 | 0.84 | MAOA (0.40) | CYP1A2CYP19A1CYP2C9CYP2C19PRSS1 | |
| SCHEMBL14806854 | 0.84 | MAOA (0.40) | CYP1A2CYP19A1CYP2C9CYP2C19PRSS1 | |
| SCHEMBL14806861 | 0.83 | MAOA (0.39) | CYP1A2CYP19A1CYP2C9CYP2C19PRSS1 | |
| SCHEMBL2199999 | 0.78 | TSHR (0.44) | SMN1; SMN2CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL8908445 | 0.78 | L3MBTL1 (0.53) | CYP1A2CYP2C19 | |
| SCHEMBL14806866 | 0.78 | CHRNA7 (0.44) | — | |
| SCHEMBL14806868 | 0.78 | TSHR (0.44) | SMN1; SMN2CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL585410 | 0.78 | TSHR (0.44) | SMN1; SMN2CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL7614855 | 0.77 | LMNA (0.49) | CYP1A2KDM4EDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684948-B1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | DIAGNOSTIKFORSCHUNG INST (DE) | 1997-10-22 | — | — | EP | disclosed |
| WO-1994019352-A1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) | 1994-09-01 | — | — | WO | disclosed |