Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30340615 | 0.84 | ALDH1A1 (0.56) | HTR2AHTR2CALDH1A1GAAPKM | |
| SCHEMBL3071409 | 0.83 | HTR2A (0.56) | HTR2AHTR2CALDH1A1GAAPKM | |
| SCHEMBL8905312 | 0.79 | HTR2A (0.53) | HTR2AHTR2CALDH1A1GAAPKM | |
| SCHEMBL13041061 | 0.78 | HTR2A (0.56) | HTR2AHTR2CALDH1A1GAAPKM | |
| SCHEMBL12919994 | 0.77 | HTR2A (0.53) | HTR2AHTR2CALDH1A1GAAPKM | |
| SCHEMBL20897096 | 0.77 | HTR2A (0.45) | HTR2AHTR2CALDH1A1GAAPKM | |
| SCHEMBL8905316 | 0.75 | HTR2A (0.49) | HTR2AHTR2CALDH1A1GAAPKM | |
| SCHEMBL19193260 | 0.74 | HTR2A (0.51) | HTR2AHTR2CALDH1A1GAAPKM | |
| SCHEMBL19099129 | 0.74 | HTR2A (0.51) | HTR2AHTR2CALDH1A1GAAPKM | |
| SCHEMBL30039910 | 0.73 | HTR2A (0.49) | HTR2AHTR2CALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997045408-A1 | HERBICIDAL INDOLINES | ZENECA LIMITED (GB) | 1997-12-04 | — | — | WO | claimed |