Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.65 |
| ▸ | BACE1 | P56817 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.60 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909767 | 1.00 | LTA4H (0.65) | LTA4HBACE1HRH3SLC6A1HTR7 | |
| Hydrochloric Acid SCHEMBL8910515 | 0.99 | LTA4H (0.64) | LTA4HBACE1HRH3SLC6A1 | |
| Hydrochloric Acid SCHEMBL8910524 | 0.99 | LTA4H (0.64) | LTA4HBACE1HRH3SLC6A1 | |
| SCHEMBL9079027 | 0.89 | SLC6A1 (0.67) | SLC6A1 | |
| SCHEMBL8788557 | 0.89 | SLC6A1 (0.67) | SLC6A1 | |
| Hydrochloric Acid SCHEMBL8910227 | 0.88 | SLC6A1 (0.66) | SLC6A1 | |
| Hydrochloric Acid SCHEMBL8910236 | 0.88 | SLC6A1 (0.66) | SLC6A1 | |
| SCHEMBL8910362 | 0.87 | L3MBTL1 (0.63) | LTA4HBACE1HRH3HTR7 | |
| SCHEMBL8910367 | 0.87 | L3MBTL1 (0.63) | LTA4HBACE1HRH3HTR7 | |
| Oxalic Acid SCHEMBL8789284 | 0.87 | SLC6A1 (0.65) | SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635518-A | TREATING CENTRAL NERVOUS SYSTEM AILMENT RELATED TO 4-AMINOBUTYRIC ACID UPTAKE | NOVO NORDISK A/S (DK) | 1997-06-03 | — | — | US | claimed |
| EP-0705247-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 1996-04-10 | — | — | EP | claimed |
| WO-1995000485-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 1995-01-05 | — | — | WO | claimed |