Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910607 | 0.90 | BPTF (0.49) | SIGMAR1HIF1ABPTFHSD11B1TSHR | |
| SCHEMBL8910246 | 0.80 | SIGMAR1 (0.43) | SIGMAR1HIF1ABPTFHSD11B1TSHR | |
| SCHEMBL5499445 | 0.74 | SIGMAR1 (0.47) | SIGMAR1HIF1A | |
| SCHEMBL8105933 | 0.73 | SIGMAR1 (0.56) | SIGMAR1HIF1A | |
| SCHEMBL8105937 | 0.73 | SIGMAR1 (0.56) | SIGMAR1HIF1A | |
| SCHEMBL8908632 | 0.73 | SIGMAR1 (0.56) | SIGMAR1HIF1A | |
| SCHEMBL8910605 | 0.73 | SIGMAR1 (0.60) | SIGMAR1HIF1AHSD11B1 | |
| SCHEMBL8909799 | 0.72 | SIGMAR1 (0.43) | SIGMAR1HIF1A | |
| SCHEMBL8105781 | 0.71 | SIGMAR1 (0.56) | SIGMAR1HIF1A | |
| SCHEMBL8099508 | 0.71 | SIGMAR1 (0.58) | SIGMAR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658923-A | USED IN TREATING DISEASES RELATED TO SIGMA-RECEPTOR, SUCH AS SCHIZOPHRENIA | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-08-19 | — | — | US | disclosed |