Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910605 | 0.87 | SIGMAR1 (0.60) | SIGMAR1HIF1A | |
| SCHEMBL8105933 | 0.82 | SIGMAR1 (0.56) | SIGMAR1HIF1AOPRM1OPRL1 | |
| SCHEMBL8105937 | 0.82 | SIGMAR1 (0.56) | SIGMAR1HIF1AOPRM1OPRL1 | |
| SCHEMBL8908632 | 0.82 | SIGMAR1 (0.56) | SIGMAR1HIF1AOPRM1OPRL1 | |
| SCHEMBL8908767 | 0.82 | SIGMAR1 (0.46) | SIGMAR1HIF1A | |
| SCHEMBL8909813 | 0.77 | SIGMAR1 (0.45) | SIGMAR1HIF1A | |
| SCHEMBL8908667 | 0.75 | SIGMAR1 (0.40) | SIGMAR1OPRM1OPRL1 | |
| SCHEMBL8099508 | 0.75 | SIGMAR1 (0.58) | SIGMAR1 | |
| SCHEMBL5499445 | 0.75 | SIGMAR1 (0.47) | SIGMAR1HIF1AAPOBEC3ACTDSP1APOBEC3G | |
| SCHEMBL8103954 | 0.73 | SIGMAR1 (0.75) | SIGMAR1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658923-A | USED IN TREATING DISEASES RELATED TO SIGMA-RECEPTOR, SUCH AS SCHIZOPHRENIA | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-08-19 | — | — | US | disclosed |