SCHEMBL890987

SCHEMBL890987

COC(=O)c1cccc(O)c1OC(=O)c1cc(O)cc(O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.54
CA1 P00915 6/20 0.54
CA2 P00918 6/20 0.54
CA7 P43166 6/20 0.54
CA9 Q16790 6/20 0.54
CA14 Q9ULX7 6/20 0.54
LMNA P02545 3/20 0.51
TSHR P16473 1/20 0.51
PDK2 Q15119 1/20 0.45
PDK4 Q16654 1/20 0.45
PTGS2 P35354 1/20 0.44
SLC6A3 Q01959 1/20 0.44
HPGD P15428 1/20 0.43
PRKCG P05129 1/20 0.41
PRKCB P05771 1/20 0.41
PRKCA P17252 1/20 0.41
PRKACA P17612 1/20 0.41
PRKACG P22612 1/20 0.41
PRKACB P22694 1/20 0.41
PRKCH P24723 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3776778 0.85 SLC6A3 (0.62) CA12CA1CA2CA7CA9
SCHEMBL4385204 0.80 LMNA (0.59) CA12CA1CA2CA7CA9
Methyl 3-Hydroxy-2-Methoxybenzoate SCHEMBL1050662 0.77 LMNA (0.66) CA12CA1CA2CA7CA9
Methyl 3,5-Dihydroxybenzoate SCHEMBL890986 0.77 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL19719015 0.76 LMNA (0.54) CA12CA1CA2CA7CA9
SCHEMBL15495958 0.75 LMNA (0.53) CA12CA1CA2CA7CA9
SCHEMBL27443722 0.74 SLC6A3 (0.70) CA1CA2CA9LMNATSHR
SCHEMBL4395970 0.73 TSHR (0.56) CA12CA1CA2CA7CA9
Methyl 3,5-Dihydroxybenzoate SCHEMBL38869 0.73 CA1 (1.00) CA12CA1CA2CA7CA9
SCHEMBL5331876 0.72 TSHR (0.58) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9933721-B2 Electrophotographic toner and method for producing the same TOSHIBA TEC KABUSHIKI KAISHA (JP) 2018-04-03 US disclosed
US-9500969-B2 Electrophotographic toner and method for producing the same TOSHIBA TEC KABUSHIKI KAISHA (JP) 2016-11-22 US disclosed
US-20160116855-A1 ELECTROPHOTOGRAPHIC TONER AND METHOD FOR PRODUCING THE SAME TOSHIBA TEC KABUSHIKI KAISHA (JP) 2016-04-28 US disclosed
US-20150268571-A1 ELECTROPHOTOGRAPHIC TONER AND METHOD FOR PRODUCING THE SAME TOSHIBA TEC KABUSHIKI KAISHA (JP) 2015-09-24 US disclosed
US-20120082928-A1 ELECTROPHOTOGRAPHIC TONER AND METHOD FOR PRODUCING THE SAME TOSHIBA TEC KABUSHIKI KAISHA (JP) 2012-04-05 US disclosed