Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909628 | 0.83 | LTB4R (0.34) | LTB4RLTB4R2 | |
| SCHEMBL9049665 | 0.82 | LTB4R (0.32) | LTB4RLTB4R2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8910701 | 0.81 | PDE4A (0.31) | — | |
| SCHEMBL8909963 | 0.78 | LTB4R (0.51) | LTB4RLTB4R2 | |
| SCHEMBL9048895 | 0.78 | LTB4R (0.51) | LTB4RLTB4R2 | |
| SCHEMBL9051279 | 0.77 | — | — | |
| SCHEMBL9046790 | 0.77 | — | — | |
| SCHEMBL9050969 | 0.77 | — | — | |
| SCHEMBL8909946 | 0.75 | LTB4R (0.45) | LTB4RLTB4R2 | |
| SCHEMBL9050982 | 0.73 | THRB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639902-A | FOR TREATING PSORIASIS | ADIR ET COMPAGNIE (FR) | 1997-06-17 | — | — | US | disclosed |
| EP-0611755-B1 | (Cyclohexyl)-alken compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1996-07-10 | — | — | EP | disclosed |
| EP-0611755-A1 | (Cyclohexyl)-alken compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-08-24 | — | — | EP | disclosed |