Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909628 | 0.94 | LTB4R (0.34) | LTB4RLTB4R2 | |
| SCHEMBL8910179 | 0.82 | LTB4R (0.33) | LTB4RLTB4R2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9051369 | 0.78 | LTB4R (0.50) | LTB4RLTB4R2 | |
| SCHEMBL8910701 | 0.76 | PDE4A (0.31) | — | |
| SCHEMBL8909237 | 0.74 | LTB4R (0.44) | LTB4RLTB4R2 | |
| SCHEMBL9050982 | 0.74 | THRB (0.32) | — | |
| SCHEMBL9050969 | 0.74 | — | — | |
| SCHEMBL9051279 | 0.74 | — | — | |
| SCHEMBL9046790 | 0.74 | — | — | |
| SCHEMBL9051549 | 0.72 | LTB4R (0.52) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611755-B1 | (Cyclohexyl)-alken compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1996-07-10 | — | — | EP | disclosed |