Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.92 |
| ▸ | RAB9A | P51151 | 3/20 | 0.92 |
| ▸ | MEN1 | O00255 | 2/20 | 0.92 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.92 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.82 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.71 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.68 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.68 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.67 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.67 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.64 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344166 | 0.96 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2AFFAR1 | |
| SCHEMBL31432724 | 0.96 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2AFFAR1 | |
| SCHEMBL8768933 | 0.96 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2AFFAR1 | |
| SCHEMBL26953087 | 0.91 | PTPN1 (0.88) | NPC1RAB9AMEN1KMT2AFFAR1 | |
| SCHEMBL24202631 | 0.91 | SIRT1 (0.83) | NPC1RAB9AMEN1KMT2AFFAR1 | |
| N-Phenylbenzamide SCHEMBL5402750 | 0.91 | SIRT1 (0.83) | NPC1RAB9AMEN1KMT2AFFAR1 | |
| N-Phenylbenzamide SCHEMBL31966 | 0.91 | SIRT1 (0.83) | NPC1RAB9AMEN1KMT2AFFAR1 | |
| SCHEMBL1315526 | 0.91 | PTPN1 (0.87) | NPC1RAB9AMEN1KMT2AFFAR1 | |
| SCHEMBL14715824 | 0.89 | NPC1 (0.88) | NPC1RAB9AMEN1KMT2AFFAR1 | |
| SCHEMBL18103163 | 0.89 | NPC1 (0.88) | NPC1RAB9AMEN1KMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672750-A | Preparation of aromatic amides from carbon monoxide, an amine and an aromatic chloride | EASTMAN CHEMICAL COMPANY (US) | 1997-09-30 | — | — | US | disclosed |