SCHEMBL8910470

SCHEMBL8910470

CNC(=O)C(Cc1ccccc1F)N(C)C(=O)C(Cc1ccc2ccccc2c1)NC(=O)c1cccc(CCN)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN2 P17706 2/20 0.45
PTPN1 P18031 2/20 0.45
CDC25B P30305 2/20 0.45
CTSL P07711 2/20 0.42
CTSS P25774 2/20 0.42
ALB P02768 1/20 0.41
IL2 P60568 1/20 0.41
MMP9 P14780 2/20 0.41
MMP8 P22894 2/20 0.41
CTSB P07858 1/20 0.39
CTSK P43235 1/20 0.39
FCER2 P06734 1/20 0.39
CA2 P00918 1/20 0.39
PIN1 Q13526 3/20 0.38
F2 P00734 2/20 0.38
KLKB1 P03952 2/20 0.37
TACR1 P25103 2/20 0.37
KLK1 P06870 1/20 0.37
MMP2 P08253 1/20 0.37
MME P08473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8525046 0.88 CTSL (0.51) PTPN1CTSLCTSSMMP9MMP8
SCHEMBL6317658 0.83 MMP9 (0.45) PTPN2PTPN1CDC25BALBIL2
SCHEMBL6316968 0.83 MMP9 (0.45) PTPN2PTPN1CDC25BALBIL2
SCHEMBL6318936 0.82 GHSR (0.38) PTPN2PTPN1CDC25BMMP9MMP8
SCHEMBL6846555 0.81 MMP9 (0.43) PTPN1CTSLCTSSALBIL2
SCHEMBL6317650 0.78 CYP3A4 (0.40) PTPN2PTPN1CDC25BMMP9MMP8
SCHEMBL6318694 0.76 PTPN1 (0.38) PTPN2PTPN1CDC25BMMP9MMP8
SCHEMBL8171207 0.75 GRIA1 (0.48) CTSLCTSSCTSBCTSKF2
SCHEMBL8173978 0.75 PRSS1 (0.43) PTPN1CTSLCTSSMMP9MMP8
SCHEMBL14977961 0.74 PRSS1 (0.47) CTSLCTSSCTSBCTSKFCER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997023508-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1997-07-03 WO disclosed