Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | GIPR | P48546 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910234 | 0.90 | ALDH1A1 (0.41) | MCHR1ALDH1A1KMT2AMAPTNR1H2 | |
| SCHEMBL9137878 | 0.88 | MCHR1 (0.41) | MCHR1LIMK1ALDH1A1KMT2ACACNA1G | |
| SCHEMBL8574886 | 0.86 | ALDH1A1 (0.41) | MCHR1IDO1ALDH1A1KMT2AMAPT | |
| SCHEMBL8911091 | 0.81 | ALDH1A1 (0.40) | IDO1ALDH1A1MAPTCACNA1HSMN1; SMN2 | |
| SCHEMBL8911497 | 0.81 | PSMB5 (0.38) | MCHR1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL8577375 | 0.80 | ALDH1A1 (0.37) | MCHR1IDO1ALDH1A1KMT2AMAPT | |
| SCHEMBL8911120 | 0.79 | NR1H2 (0.35) | MCHR1LIMK1ALDH1A1MAPTNR1H2 | |
| SCHEMBL8911295 | 0.78 | ALDH1A1 (0.35) | ALDH1A1KMT2AMAPTNR1H2NR1H3 | |
| SCHEMBL8911137 | 0.78 | GCGR (0.36) | MCHR1ALDH1A1KMT2ANR1H2NR1H3 | |
| SCHEMBL8911516 | 0.77 | CYP11B1 (0.38) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |