Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911120 | 0.91 | NR1H2 (0.35) | GCGRHTTNR1H2NR1H3CYP11B1 | |
| SCHEMBL8912581 | 0.88 | CYP11B1 (0.37) | GCGRCYP11B1CYP11B2CYP19A1CHEK1 | |
| SCHEMBL8574886 | 0.86 | ALDH1A1 (0.41) | CYP11B1CYP11B2KMT2APOLBALDH1A1 | |
| SCHEMBL8911516 | 0.82 | CYP11B1 (0.38) | CYP11B1CYP11B2KMT2AEP300 | |
| SCHEMBL8911497 | 0.81 | PSMB5 (0.38) | CYP11B1CYP11B2POLBALDH1A1MCHR1 | |
| SCHEMBL8911091 | 0.81 | ALDH1A1 (0.40) | CYP11B1CYP11B2POLBALDH1A1RORC | |
| SCHEMBL8912989 | 0.80 | CYP11B1 (0.40) | CYP11B1CYP11B2CYP19A1EP300 | |
| SCHEMBL8913188 | 0.80 | PTGER1 (0.37) | CYP11B1CYP11B2CYP19A1KMT2ALMNA | |
| SCHEMBL8911295 | 0.78 | ALDH1A1 (0.35) | NR1H2NR1H3KMT2AALDH1A1HDAC1 | |
| SCHEMBL8910536 | 0.78 | MCHR1 (0.38) | GCGRNR1H2NR1H3KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |