Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574886 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KMT2ASMN1; SMN2GAATDP1 | |
| SCHEMBL8911120 | 0.79 | NR1H2 (0.35) | ALDH1A1NR1H2NR1H3MAPT | |
| SCHEMBL8910234 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL8911137 | 0.78 | GCGR (0.36) | ALDH1A1KMT2ANR1H2NR1H3HDAC1 | |
| SCHEMBL8910536 | 0.78 | MCHR1 (0.38) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL8911497 | 0.76 | PSMB5 (0.38) | ALDH1A1SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL8911516 | 0.76 | CYP11B1 (0.38) | KMT2AMEN1TSHR | |
| SCHEMBL8911091 | 0.74 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL8912989 | 0.74 | CYP11B1 (0.40) | TSHR | |
| SCHEMBL8913010 | 0.70 | ALDH1A1 (0.36) | ALDH1A1KMT2AMEN1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |