Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.43 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906153 | 0.96 | RXRA (0.45) | RXRARXRBRXRGAGTR1LTB4R2 | |
| SCHEMBL8905607 | 0.92 | RXRA (0.42) | RXRARXRBRXRG | |
| SCHEMBL8905251 | 0.87 | RXRA (0.53) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8906010 | 0.84 | RXRA (0.49) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7208758 | 0.84 | RARB (0.53) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7208752 | 0.84 | RARB (0.53) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7212209 | 0.80 | RXRA (0.53) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7212216 | 0.80 | RXRA (0.53) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7208504 | 0.77 | RXRA (0.48) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7208507 | 0.77 | RXRA (0.48) | RXRARXRBRXRGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | disclosed |