Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5957612 | 0.82 | SLC6A2 (0.38) | CHRM3HTR7SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28475644 | 0.78 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| SCHEMBL30904665 | 0.76 | SLC6A3 (0.47) | SLC6A2SLC6A4SLC6A3BCL2BAK1 | |
| SCHEMBL7115205 | 0.76 | HRH1 (0.42) | CHRM3SLC6A2SLC6A4SLC6A3ATM | |
| SCHEMBL1959454 | 0.75 | HTR7 (0.40) | HTR7SLC6A2SLC6A4SLC6A3ATM | |
| SCHEMBL27749112 | 0.75 | HTR2C (0.48) | HTR7TAAR1HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL5957371 | 0.75 | HRH1 (0.43) | CHRM3SLC6A2SLC6A4SLC6A3ATM | |
| SCHEMBL10413244 | 0.72 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL6926417 | 0.72 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL22285003 | 0.72 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |