Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5957371 | 0.99 | HRH1 (0.43) | HRH1TDP1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7950557 | 0.85 | TDP1 (0.41) | HRH1TDP1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL6634458 | 0.85 | CHRM3 (0.38) | HRH1TDP1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL30904665 | 0.78 | SLC6A3 (0.47) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8910673 | 0.76 | CHRM3 (0.41) | HRH1SLC6A2SLC6A3SLC6A4HRH2 | |
| SCHEMBL6711052 | 0.75 | TDP1 (0.39) | TDP1MITF | |
| SCHEMBL6482143 | 0.75 | HRH1 (0.54) | HRH1TDP1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL219876 | 0.74 | HRH1 (0.59) | HRH1TDP1SLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL5957369 | 0.74 | HRH1 (0.55) | HRH1TDP1SLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL5686168 | 0.74 | HRH1 (0.60) | HRH1TDP1SLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196409-B1 | RESPIRATORY SYNCYTIAL VIRUS REPLICATION INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2004-02-04 | — | — | EP | disclosed |