Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | SLC6A7 | Q99884 | 9/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910380 | 0.88 | NPC1 (0.33) | MCHR1 | |
| SCHEMBL8912610 | 0.80 | PDE4A (0.38) | — | |
| SCHEMBL8912125 | 0.79 | HDAC1 (0.33) | — | |
| SCHEMBL8912193 | 0.77 | PLAU (0.35) | — | |
| SCHEMBL8910431 | 0.76 | ESR2 (0.35) | PARP10PARP11 | |
| SCHEMBL8910275 | 0.65 | TAAR1 (0.43) | TAAR1PARP10PARP11MAOBPGR | |
| SCHEMBL31491189 | 0.62 | TAAR1 (0.71) | TAAR1MAOBPGRTDP2 | |
| SCHEMBL16394285 | 0.62 | TAAR1 (0.71) | TAAR1MAOBPGRTDP2 | |
| SCHEMBL11480601 | 0.62 | NPC1 (0.50) | SLC6A3 | |
| SCHEMBL11480596 | 0.62 | NPC1 (0.50) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |