Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911057 | 0.88 | ACHE (0.33) | NPC1RAB9AACHEMCHR1 | |
| SCHEMBL8910792 | 0.88 | TAAR1 (0.39) | MCHR1 | |
| SCHEMBL8912125 | 0.85 | HDAC1 (0.33) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8912610 | 0.81 | PDE4A (0.38) | — | |
| SCHEMBL8910431 | 0.74 | ESR2 (0.35) | NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL8912193 | 0.73 | PLAU (0.35) | NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL7082654 | 0.68 | NPC1 (0.68) | NPC1RAB9AHPGDSMN1; SMN2SLC2A1 | |
| SCHEMBL6168784 | 0.68 | NPC1 (0.68) | NPC1RAB9AHPGDSMN1; SMN2SLC2A1 | |
| SCHEMBL7782342 | 0.66 | NPC1 (0.47) | NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL27570052 | 0.66 | GSK3B (0.57) | NPC1RAB9AHPGDSMN1; SMN2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |