Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CTSA | P10619 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910431 | 0.75 | ESR2 (0.35) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL8911057 | 0.72 | ACHE (0.33) | NPC1RAB9AKDM4E | |
| SCHEMBL8912610 | 0.70 | PDE4A (0.38) | ALDH1A1HDAC1KDM4E | |
| SCHEMBL8912125 | 0.69 | HDAC1 (0.33) | ALDH1A1MAPTSMN1; SMN2HDAC1 | |
| SCHEMBL8911116 | 0.63 | PLAU (0.37) | PLAUALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3265125 | 0.61 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL28046856 | 0.60 | KMO (0.50) | PLAUCTSAHDAC1USP30 | |
| SCHEMBL27882253 | 0.60 | EGFR (0.50) | PLAUALDH1A1KMT2AMAPTCTSA | |
| SCHEMBL725162 | 0.60 | KMO (0.62) | PLAUALDH1A1MAPTSMN1; SMN2HDAC1 | |
| SCHEMBL7524323 | 0.59 | NPC1 (0.45) | ALDH1A1MEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |