Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19490331 | 0.76 | ADORA3 (0.60) | KDM4EMAPTBACE1KMT2AADORA3 | |
| SCHEMBL28965238 | 0.76 | LMNA (0.47) | KDM4EMAPTLMNAACHEPKM | |
| SCHEMBL13258542 | 0.74 | CYP3A4 (0.53) | ELANEKDM4EMAPK1MAPTLMNA | |
| SCHEMBL22373561 | 0.73 | ELANE (0.51) | ELANEKDM4EMAPK1MAPTLMNA | |
| SCHEMBL12121608 | 0.71 | KDM4E (0.68) | ELANEKDM4EMAPK1MAPTLMNA | |
| SCHEMBL19484788 | 0.71 | MAPT (0.43) | MAPTLMNABACE1KMT2ATSHR | |
| SCHEMBL4776733 | 0.70 | LMNA (0.60) | ELANEKDM4EMAPTLMNABACE1 | |
| SCHEMBL6537219 | 0.70 | ADORA3 (0.49) | KDM4EMAPK1MAPTLMNABACE1 | |
| SCHEMBL5582943 | 0.69 | ACHE (0.58) | ELANEKDM4EMAPK1MAPTLMNA | |
| SCHEMBL28961586 | 0.68 | CYP3A4 (0.48) | ELANEKDM4EMAPK1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597854-A | PHOTOGRAPHIC APPLICATIONS, COATINGS, BINDERS, POLYMERS, TRIAZINE OR PYRIMIDINE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1997-01-28 | — | — | US | disclosed |
| EP-0711804-A2 | Latent light stabilizers | CIBA-GEIGY AG (CH) | 1996-05-15 | — | — | EP | disclosed |