Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19367869 | 0.77 | CES1 (0.59) | CES2CES1SLC6A3PLOD2HDAC1 | |
| SCHEMBL8911789 | 0.76 | PLOD2 (0.46) | CES2CES1SLC6A3PLOD2KDM4E | |
| SCHEMBL8912196 | 0.73 | PLOD2 (0.44) | CES2CES1SLC6A3PLOD2KDM4E | |
| SCHEMBL8911868 | 0.72 | PLOD2 (0.42) | CES2CES1SLC6A3PLOD2KDM4E | |
| SCHEMBL8911819 | 0.71 | PLOD2 (0.49) | CES2CES1SLC6A3PLOD2HDAC3 | |
| SCHEMBL7220761 | 0.71 | CES1 (0.52) | CES2CES1SLC6A3PLOD2HDAC1 | |
| SCHEMBL3539680 | 0.71 | CES2 (0.39) | CES2CES1SLC6A3HDAC3HDAC4 | |
| SCHEMBL8911964 | 0.71 | PLOD2 (0.41) | CES2CES1SLC6A3PLOD2KDM4E | |
| SCHEMBL8911872 | 0.70 | PLOD2 (0.47) | CES2CES1SLC6A3PLOD2HDAC3 | |
| SCHEMBL8911577 | 0.69 | PLOD2 (0.46) | CES2CES1SLC6A3PLOD2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618547-A | ADMINISTERING PERFLUOROALKYL GROUP-CONTAINING PHENYL PROPANEDIONE DERIVATIVES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-04-08 | — | — | US | disclosed |
| US-4870109-A | ANIMAL HUSBANDRY | ELI LILLY AND COMPANY (US) | 1989-09-26 | — | — | US | disclosed |
| EP-0317275-A2 | Control of ectoparasites | BRITISH TECHNOLOGY GROUP USA INC. (US) | 1989-05-24 | — | — | EP | disclosed |