Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.36 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | VNN1 | O95497 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911964 | 0.91 | PLOD2 (0.41) | PLOD2CES2CES1SLC6A3PLOD3 | |
| SCHEMBL8911868 | 0.86 | PLOD2 (0.42) | PLOD2CES2CES1SLC6A3PLOD3 | |
| SCHEMBL8911789 | 0.83 | PLOD2 (0.46) | PLOD2CES2CES1SLC6A3PLOD3 | |
| SCHEMBL8911819 | 0.83 | PLOD2 (0.49) | PLOD2CES2CES1SLC6A3PLOD3 | |
| SCHEMBL8911872 | 0.81 | PLOD2 (0.47) | PLOD2CES2CES1SLC6A3PLOD3 | |
| SCHEMBL8911577 | 0.80 | PLOD2 (0.46) | PLOD2CES2CES1SLC6A3PLOD3 | |
| SCHEMBL8912767 | 0.79 | PLOD2 (0.45) | PLOD2CES2CES1SLC6A3PLOD3 | |
| SCHEMBL8910631 | 0.77 | GPR139 (0.36) | PLOD2PLOD3PLOD1 | |
| SCHEMBL19367869 | 0.74 | CES1 (0.59) | PLOD2CES2CES1SLC6A3HTT | |
| SCHEMBL8912732 | 0.74 | CES2 (0.43) | PLOD2CES2PLOD3PLOD1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618547-A | ADMINISTERING PERFLUOROALKYL GROUP-CONTAINING PHENYL PROPANEDIONE DERIVATIVES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-04-08 | — | — | US | disclosed |
| US-4870109-A | ANIMAL HUSBANDRY | ELI LILLY AND COMPANY (US) | 1989-09-26 | — | — | US | disclosed |
| EP-0317275-A2 | Control of ectoparasites | BRITISH TECHNOLOGY GROUP USA INC. (US) | 1989-05-24 | — | — | EP | disclosed |