Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.54 |
| ▸ | HPRT1 | P00492 | 8/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.46 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172847 | 0.89 | HPRT1 (0.55) | FGFR1HPRT1SLC22A6CYP3A4TYMP | |
| SCHEMBL15516660 | 0.89 | HPRT1 (0.55) | FGFR1HPRT1SLC22A6CYP3A4TYMP | |
| SCHEMBL29450587 | 0.89 | HPRT1 (0.55) | FGFR1HPRT1SLC22A6CYP3A4TYMP | |
| SCHEMBL8421102 | 0.84 | CYP3A4 (0.52) | FGFR1HPRT1SLC22A6CYP3A4P2RY1 | |
| SCHEMBL8911148 | 0.84 | PDE8A (0.45) | HPRT1CYP3A4 | |
| SCHEMBL66563 | 0.83 | CYP3A4 (0.73) | FGFR1HPRT1SLC22A6CYP3A4 | |
| SCHEMBL29437221 | 0.83 | CYP3A4 (0.73) | FGFR1HPRT1SLC22A6CYP3A4 | |
| SCHEMBL385752 | 0.83 | CYP3A4 (0.73) | FGFR1HPRT1SLC22A6CYP3A4 | |
| SCHEMBL97303 | 0.80 | HPRT1 (0.51) | FGFR1HPRT1SLC22A6CYP3A4 | |
| SCHEMBL173060 | 0.80 | HPRT1 (0.81) | HPRT1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35558-E | (2R)-2-[di(2-propyl)phosphonyylmethoxy]-3-P-toluenesulfonyloxy-1-trimethylacetoxypropane, its preparation and use | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1997-07-08 | — | — | US | disclosed |
| US-5130427-A | Viricides formed by etherification, esterification and reaction with a phosphonate containing compound | CESKOSLOVENSKA AKADEMIE VED (CS) | 1992-07-14 | — | — | US | disclosed |
| EP-0470809-A1 | Antiviral nucleosides, compounds useful in their preparation and processes of making them | Ceskoslovenska akademie ved (CS) | 1992-02-12 | — | — | EP | disclosed |