Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 11/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | TYMP | P19971 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450587 | 1.00 | HPRT1 (0.55) | HPRT1CYP3A4FGFR1SLC22A6CDK1 | |
| SCHEMBL172847 | 1.00 | HPRT1 (0.55) | HPRT1CYP3A4FGFR1SLC22A6CDK1 | |
| SCHEMBL97303 | 0.91 | HPRT1 (0.51) | HPRT1CYP3A4FGFR1SLC22A6CDK1 | |
| SCHEMBL14669210 | 0.90 | CYP3A4 (0.53) | HPRT1CYP3A4FGFR1SLC22A6CDK1 | |
| SCHEMBL14669198 | 0.90 | CYP3A4 (0.53) | HPRT1CYP3A4FGFR1SLC22A6CDK1 | |
| SCHEMBL14669190 | 0.90 | CYP3A4 (0.53) | HPRT1CYP3A4FGFR1SLC22A6CDK1 | |
| SCHEMBL3860363 | 0.90 | HPRT1 (0.56) | HPRT1CYP3A4FGFR1SLC22A6CDK1 | |
| SCHEMBL29624179 | 0.90 | HPRT1 (0.56) | HPRT1CYP3A4FGFR1SLC22A6CDK1 | |
| SCHEMBL9193126 | 0.90 | HPRT1 (0.56) | HPRT1CYP3A4FGFR1SLC22A6CDK1 | |
| SCHEMBL8911145 | 0.89 | FGFR1 (0.54) | HPRT1CYP3A4FGFR1SLC22A6TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016820-A1 | Lipid Disulfide Prodrugs and Uses Related Thereto | UNIV EMORY (US) | 2024-01-18 | — | — | US | disclosed |
| US-11801255-B2 | Lipid disulfide prodrugs and uses related thereto | EMORY UNIVERSITY (US) | 2023-10-31 | — | — | US | disclosed |
| US-20210338696-A1 | Lipid Disulfide Prodrugs and Uses Related Thereto | UNIV EMORY (US) | 2021-11-04 | — | — | US | disclosed |
| US-10688112-B2 | Lipid disulfide prodrugs and uses related thereto | EMORY UNIVERSITY (US) | 2020-06-23 | — | — | US | disclosed |
| US-20190015432-A1 | Lipid Disulfide Prodrugs and Uses Related Thereto | EMORY UNIVERSITY | 2019-01-17 | — | — | US | disclosed |
| WO-2014033688-A1 | A PROCESS FOR THE PREPARATION OF (R)-9-[2-(PHOSPHONOMETH-OXY)PROPYL]ADENINE (PMPA) | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2014-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338696-A1 | Lipid Disulfide Prodrugs and Uses Related Thereto | SMPD1, SGMS1, GSTO1 | HPRT1 122/4885CYP3A4 601/4885FGFR1 3777/4885 |
| US-20240016820-A1 | Lipid Disulfide Prodrugs and Uses Related Thereto | SMPD1, SGMS1, SGMS2 | HPRT1 149/4885CYP3A4 612/4885FGFR1 3912/4885 |
| US-10688112-B2 | Lipid disulfide prodrugs and uses related thereto | SMPD1, SGMS1, GSTO1 | HPRT1 122/4885CYP3A4 601/4885FGFR1 3777/4885 |
| US-11801255-B2 | Lipid disulfide prodrugs and uses related thereto | SMPD1, SGMS1, GSTO1 | HPRT1 122/4885CYP3A4 601/4885FGFR1 3777/4885 |
| US-20190015432-A1 | Lipid Disulfide Prodrugs and Uses Related Thereto | SMPD1, SGMS1, GSTO1 | HPRT1 122/4885CYP3A4 601/4885FGFR1 3777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.