Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016127 | 0.81 | HSP90AA1 (0.39) | TDP1LMNAMAPTMAPK1NPSR1 | |
| SCHEMBL25174362 | 0.81 | HSP90AA1 (0.39) | TDP1LMNAMAPTMAPK1NPSR1 | |
| SCHEMBL6418102 | 0.81 | HSP90AA1 (0.39) | TDP1LMNAMAPTMAPK1NPSR1 | |
| SCHEMBL5499677 | 0.79 | LMNA (0.47) | TDP1LMNA | |
| SCHEMBL2428644 | 0.79 | LMNA (0.47) | TDP1LMNA | |
| SCHEMBL6090753 | 0.75 | HPGD (0.45) | TDP1LMNAMAPTALDH1A1 | |
| SCHEMBL6379933 | 0.75 | HPGD (0.45) | TDP1LMNAMAPTALDH1A1 | |
| SCHEMBL9798372 | 0.74 | TDP1 (0.47) | TDP1NAAALMNA | |
| SCHEMBL9804059 | 0.73 | CYP19A1 (0.47) | TDP1LMNAMAPTMAPK1KDM4E | |
| SCHEMBL3359317 | 0.72 | LMNA (0.46) | TDP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5598005-A | Non-destructive method for determining the extent of cure of a polymerizing material and the solidification of a thermoplastic polymer based on wavelength shift of fluroescence | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE COMMERCE (US) | 1997-01-28 | — | — | US | claimed |