Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6379933 | 1.00 | HPGD (0.45) | HPGDGAALMNATDP1HDAC1 | |
| SCHEMBL5499677 | 0.95 | LMNA (0.47) | HPGDGAALMNATDP1HDAC1 | |
| SCHEMBL2428644 | 0.95 | LMNA (0.47) | HPGDGAALMNATDP1HDAC1 | |
| SCHEMBL5128478 | 0.84 | LMNA (0.41) | HPGDGAALMNATDP1 | |
| SCHEMBL9798372 | 0.84 | TDP1 (0.47) | HPGDGAALMNATDP1CES2 | |
| SCHEMBL3359317 | 0.83 | LMNA (0.46) | LMNATDP1MAPT | |
| SCHEMBL11206642 | 0.82 | NPC1 (0.49) | HPGDLMNAALDH1A1CYP2D6MAPT | |
| SCHEMBL12411252 | 0.82 | NPC1 (0.49) | HPGDLMNAALDH1A1CYP2D6MAPT | |
| SCHEMBL27473191 | 0.79 | LMNA (0.45) | HPGDGAALMNATDP1ALDH1A1 | |
| SCHEMBL5420760 | 0.79 | P4HB (0.37) | HPGDGAALMNAHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7065277-B2 | Optical alignment of optical waveguides | AVAGO TECHNOLOGIES GENERAL IP (SINGAPORE) PTE. LTD. (SG) | 2006-06-20 | — | — | US | disclosed |
| US-20050025428-A1 | Optical alignment of optical waveguides | AVAGO TECHNOLOGIES GENERAL IP (SINGAPORE) PTE. LTD. (SG) | 2005-02-03 | — | — | US | disclosed |