⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440778 | 0.79 | LMNA (0.45) | — | |
| SCHEMBL2406587 | 0.79 | — | — | |
| SCHEMBL20606599 | 0.78 | LMNA (0.39) | — | |
| SCHEMBL444319 | 0.77 | LMNA (0.43) | — | |
| SCHEMBL440726 | 0.77 | LMNA (0.43) | — | |
| SCHEMBL439284 | 0.77 | LMNA (0.43) | — | |
| SCHEMBL443426 | 0.77 | LMNA (0.43) | — | |
| SCHEMBL8951713 | 0.74 | FDPS (0.45) | — | |
| SCHEMBL22772583 | 0.70 | KDM4E (0.36) | — | |
| SCHEMBL8331137 | 0.70 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488171-A | Phosphinate esters | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | claimed |
| US-5693799-A | Method of synthesizing an organophosphorus compound | NOVARTIS CORP. (US) | 1997-12-02 | — | — | US | disclosed |
| US-5488171-A | Phosphinate esters | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| EP-0614900-A1 | Phosphinate esters | CIBA-GEIGY AG (CH) | 1994-09-14 | — | — | EP | disclosed |