Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 8/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440778 | 0.97 | LMNA (0.45) | LMNAGRM4FDPSPGK1PGK2 | |
| SCHEMBL443426 | 0.94 | LMNA (0.43) | LMNAGRM4FDPSPGK1PGK2 | |
| SCHEMBL440726 | 0.94 | LMNA (0.43) | LMNAGRM4FDPSPGK1PGK2 | |
| SCHEMBL444319 | 0.94 | LMNA (0.43) | LMNAGRM4FDPSPGK1PGK2 | |
| SCHEMBL8951713 | 0.79 | FDPS (0.45) | FDPSGGPS1 | |
| SCHEMBL6360302 | 0.78 | GABBR2 (0.54) | LMNAFDPSMEN1TSHRKMT2A | |
| SCHEMBL8911342 | 0.77 | — | — | |
| SCHEMBL8951671 | 0.76 | LMNA (0.33) | LMNAGRM4 | |
| SCHEMBL8331137 | 0.70 | LMNA (0.38) | LMNAGRM4FDPS | |
| SCHEMBL4649888 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120064790-A1 | Ethylene Diphosphinic Acids | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-03-15 | — | — | US | disclosed |
| US-8084518-B2 | Ethylenebis(hydroxyalkylphosphinic acid) and salts thereof | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-12-27 | — | — | US | disclosed |
| US-20100093239-A1 | Ethylene Diphosphinic Acids | CLARIANT INTERNATIONAL LTD. (CH) | 2010-04-15 | — | — | US | disclosed |