Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764963 | 0.82 | NPC1 (0.54) | HPGDSMN1; SMN2NPC1RAB9AOPRM1 | |
| Hydrochloric Acid SCHEMBL10749720 | 0.81 | NPC1 (0.53) | HPGDSMN1; SMN2NPC1RAB9AOPRM1 | |
| SCHEMBL27674378 | 0.76 | OPRM1 (0.51) | HPGDSMN1; SMN2NPC1RAB9AOPRM1 | |
| SCHEMBL8316811 | 0.76 | OPRM1 (0.65) | HPGDOPRM1OPRD1OPRK1NR4A1 | |
| SCHEMBL7328025 | 0.74 | RAB9A (0.47) | HPGDSMN1; SMN2NPC1RAB9AOPRD1 | |
| SCHEMBL7496643 | 0.74 | RAB9A (0.47) | HPGDSMN1; SMN2NPC1RAB9AOPRD1 | |
| SCHEMBL8366194 | 0.71 | HPGD (0.44) | HPGDSMN1; SMN2NPC1RAB9AOPRM1 | |
| SCHEMBL5766517 | 0.69 | RAB9A (0.51) | HPGDSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL5766519 | 0.69 | RAB9A (0.51) | HPGDSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL1144315 | 0.67 | RAB9A (0.56) | HPGDSMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |