Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764963 | 0.82 | NPC1 (0.54) | HPGDRAB9ANPC1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL10749720 | 0.81 | NPC1 (0.53) | HPGDRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL7496643 | 0.74 | RAB9A (0.47) | HPGDRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL9253700 | 0.74 | OPRM1 (0.62) | HPGDRAB9ANPC1SMN1; SMN2HPGDS | |
| SCHEMBL7328025 | 0.74 | RAB9A (0.47) | HPGDRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL3438267 | 0.72 | HPGDS (0.47) | HPGDRAB9ANPC1SMN1; SMN2HPGDS | |
| SCHEMBL8911535 | 0.71 | HPGD (0.44) | HPGDRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL5766517 | 0.69 | RAB9A (0.51) | HPGDRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL5766519 | 0.69 | RAB9A (0.51) | HPGDRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL1144315 | 0.67 | RAB9A (0.56) | HPGDRAB9ANPC1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999034802-A1 | USE OF PHENYLTHIENYLMETHYLENE PIPERIDINE DERIVATIVES IN THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF DEPRESSION | AKZO NOBEL N.V. (NL) | 1999-07-15 | — | — | WO | disclosed |
| WO-1999034800-A1 | USE OF PHENYLTHIENYLMETHYLENE PIPERIDINE DERIVATIVE IN THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF MOVEMENT DISORDERS | AKZO NOBEL N.V. (NL) | 1999-07-15 | — | — | WO | disclosed |