Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SPNS2 | Q8IVW8 | 2/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911558 | 0.89 | TLR8 (0.50) | TLR8MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7553388 | 0.85 | KCNH2 (0.37) | MAPTRAB9ASMN1; SMN2NPC1STAT3 | |
| SCHEMBL7552164 | 0.85 | ESR1 (0.34) | MAPTRAB9ASMN1; SMN2NPC1STAT3 | |
| SCHEMBL7822732 | 0.82 | NPC1 (0.61) | TLR8MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7551168 | 0.81 | MAPT (0.38) | MAPTRAB9ASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL6289604 | 0.81 | TLR8 (0.55) | TLR8MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6283828 | 0.80 | NPC1 (0.59) | TLR8MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7823855 | 0.80 | CASP3 (0.61) | TLR8MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6290855 | 0.79 | TLR8 (0.54) | TLR8PSMB5S1PR4S1PR1S1PR5 | |
| SCHEMBL7555281 | 0.79 | MAPT (0.42) | MAPTRAB9ASMN1; SMN2NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708165-A1 | Liquid crystal, liquid crystal mixture and liquid crystal device comprising the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |