Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.49 |
| ▸ | NGFR | P08138 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3107966 | 0.84 | ALDH1A1 (0.54) | KDM4EHSD17B10ALDH1A1LMNAPIN1 | |
| SCHEMBL6838149 | 0.82 | KDM4E (0.56) | KDM4EHSD17B10ALDH1A1LMNAPIN1 | |
| SCHEMBL11740631 | 0.81 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1LMNAPIN1 | |
| SCHEMBL11744575 | 0.81 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1LMNAPIN1 | |
| SCHEMBL11737870 | 0.79 | KDM4E (0.49) | KDM4EHSD17B10ALDH1A1LMNAPIN1 | |
| SCHEMBL9314516 | 0.79 | KDM4E (0.60) | KDM4EHSD17B10ALDH1A1LMNAPIN1 | |
| SCHEMBL3099146 | 0.79 | CYP2C19 (0.51) | KDM4EHSD17B10ALDH1A1LMNAPIN1 | |
| SCHEMBL29425071 | 0.77 | FLT3 (0.58) | KDM4EHSD17B10ALDH1A1LMNAPIN1 | |
| SCHEMBL3110629 | 0.77 | FLT3 (0.58) | KDM4EHSD17B10ALDH1A1LMNAPIN1 | |
| SCHEMBL9278714 | 0.75 | SMAD3 (0.52) | KDM4EHSD17B10ALDH1A1LMNAPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5609649-A | Tinctorial composition for keratinous fibers containing oxidation dye precursors and couplers derived from 4-hydroxyindole, and dyeing method using them | L'OREAL (FR) | 1997-03-11 | — | — | US | claimed |
| EP-0428441-B1 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | OREAL (FR) | 1994-08-24 | — | — | EP | claimed |
| EP-0446131-B1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | OREAL (FR) | 1994-05-04 | — | — | EP | claimed |
| EP-0446131-A1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | claimed |
| CN-1051668-A | Contain the dyeing composition for keratinous fibres of oxidation colorant parent and 4-hydroxy indoxyl derivative colour former and use the staining that said composition is carried out | OREAL (FR) | 1991-05-29 | — | — | CN | claimed |
| EP-0428441-A2 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| US-5609649-A | Tinctorial composition for keratinous fibers containing oxidation dye precursors and couplers derived from 4-hydroxyindole, and dyeing method using them | L'OREAL (FR) | 1997-03-11 | — | — | US | disclosed |
| EP-0428441-B1 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | OREAL (FR) | 1994-08-24 | — | — | EP | disclosed |
| EP-0446131-B1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | OREAL (FR) | 1994-05-04 | — | — | EP | disclosed |
| EP-0446131-A1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | disclosed |
| CN-1051668-A | Contain the dyeing composition for keratinous fibres of oxidation colorant parent and 4-hydroxy indoxyl derivative colour former and use the staining that said composition is carried out | OREAL (FR) | 1991-05-29 | — | — | CN | disclosed |
| EP-0428441-A2 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | disclosed |