Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.50 |
| ▸ | RHEB | Q15382 | 6/20 | 0.48 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NGFR | P08138 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL708527 | 0.83 | GRIN1 (0.57) | KDM4ELMNAALDH1A1HSD17B10GRIN1 | |
| SCHEMBL3107966 | 0.83 | ALDH1A1 (0.54) | KDM4ELMNAALDH1A1HSD17B10GRIN1 | |
| SCHEMBL19331227 | 0.83 | CYP1A2 (0.45) | KDM4EALDH1A1HSD17B10HPGDCYP1A2 | |
| SCHEMBL8911576 | 0.81 | KDM4E (0.53) | KDM4ELMNAALDH1A1HSD17B10GRIN1 | |
| SCHEMBL19332451 | 0.80 | ALOX15 (0.57) | KDM4ELMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL11744575 | 0.80 | KDM4E (0.51) | KDM4ELMNAALDH1A1HSD17B10GRIN1 | |
| SCHEMBL6161388 | 0.80 | DAO (0.58) | KDM4ELMNAALDH1A1HSD17B10GRIN1 | |
| SCHEMBL3096730 | 0.80 | GRIN1 (0.54) | KDM4ELMNAALDH1A1HSD17B10GRIN1 | |
| SCHEMBL29425136 | 0.80 | DAO (0.58) | KDM4ELMNAALDH1A1HSD17B10GRIN1 | |
| SCHEMBL3110626 | 0.80 | KDM4E (0.59) | KDM4ELMNAALDH1A1HSD17B10GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060626-A | Indole-carboxylic carbon compounds and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1977-11-29 | — | — | US | disclosed |