Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284283 | 0.81 | AKR1C3 (0.50) | ALDH1A3ALDH1A1KMT2AALDH3A1MEN1 | |
| SCHEMBL12908043 | 0.81 | ALDH1A1 (0.58) | ALDH1A3ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL13419298 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KMT2AMAPTHTTSRD5A1 | |
| SCHEMBL13419187 | 0.79 | ALDH1A1 (0.61) | ALDH1A3ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL17543923 | 0.79 | CHRM1 (0.49) | ALDH1A3ALDH1A1KMT2AALDH3A1MEN1 | |
| SCHEMBL45211 | 0.79 | LMNA (0.39) | ALDH1A3ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7711149 | 0.78 | LMNA (0.43) | ALDH1A1 | |
| SCHEMBL17542897 | 0.78 | ALDH1A1 (0.44) | ALDH1A3ALDH1A1KMT2AALDH3A1MEN1 | |
| SCHEMBL16440154 | 0.78 | ALDH1A1 (0.48) | ALDH1A3ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL17543217 | 0.78 | ALDH1A3 (0.42) | ALDH1A3ALDH1A1KMT2AALDH3A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625046-A | Hydroxyl projecting groups for organic synthesis | KING'S COLLEGE LONDON (GB) | 1997-04-29 | — | — | US | disclosed |
| US-5436331-A | Etherification with N-aryl-4-alkoxy-1,2,5,6-tetrahydropyidine | KINGS COLLEGE LONDON (GB) | 1995-07-25 | — | — | US | disclosed |
| EP-0298982-B1 | PROTECTING GROUPS FOR ORGANIC SYNTHESIS | KING'S COLLEGE LONDON (GB) | 1991-08-28 | — | — | EP | disclosed |