Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 5/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | WHR1 | P49842 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899767 | 0.91 | PRKCQ (0.42) | KDM1AEHMT2RCOR1PRKCQSLC2A1 | |
| SCHEMBL8911894 | 0.88 | VCP (0.48) | KDM1AEHMT2RCOR1SLC2A1 | |
| SCHEMBL8900938 | 0.87 | SLC2A1 (0.44) | KDM1AEHMT2RCOR1PRKCQSLC2A1 | |
| SCHEMBL8898947 | 0.82 | TLR9 (0.51) | KDM1AEHMT2PDE5ATRIM58ADRA2A | |
| SCHEMBL8900115 | 0.81 | NPY5R (0.46) | PRKCQADRA2ANPY5R | |
| Hydrochloric Acid SCHEMBL8899118 | 0.81 | NPY5R (0.45) | PRKCQADRA2ANPY5R | |
| SCHEMBL8889968 | 0.80 | EHMT2 (0.52) | KDM1AEHMT2RCOR1SLC2A1PDE5A | |
| SCHEMBL8899747 | 0.79 | VCP (0.47) | SLC2A1 | |
| SCHEMBL8890893 | 0.78 | NPY5R (0.44) | PRKCQADRA2ANPY5R | |
| SCHEMBL8900924 | 0.76 | VCP (0.46) | KDM1AEHMT2RCOR1SLC2A1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |