Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 4/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.42 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.42 |
| ▸ | FLT3 | P36888 | 3/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899767 | 0.95 | PRKCQ (0.42) | SLC2A1KDM1AEHMT2RCOR1FLT3 | |
| SCHEMBL8900924 | 0.89 | VCP (0.46) | SLC2A1KDM1AEHMT2RCOR1FLT3 | |
| SCHEMBL8911900 | 0.87 | KDM1A (0.43) | SLC2A1KDM1AEHMT2RCOR1PRKCQ | |
| SCHEMBL8899747 | 0.83 | VCP (0.47) | SLC2A1 | |
| SCHEMBL8890083 | 0.83 | POLB (0.55) | SLC2A1KDM1AEHMT2FLT3TOP2A | |
| SCHEMBL8908343 | 0.83 | POLB (0.55) | SLC2A1KDM1AEHMT2FLT3TOP2A | |
| SCHEMBL8900115 | 0.79 | NPY5R (0.46) | PRKCQ | |
| Hydrochloric Acid SCHEMBL8899118 | 0.78 | NPY5R (0.45) | PRKCQ | |
| SCHEMBL8898707 | 0.77 | FLT3 (0.48) | SLC2A1FLT3TOP2APOLB | |
| SCHEMBL8907203 | 0.77 | FLT3 (0.50) | SLC2A1FLT3TOP2APOLBKMT5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |