Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 16/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899747 | 0.91 | VCP (0.47) | VCPSLC2A1 | |
| SCHEMBL8900924 | 0.88 | VCP (0.46) | VCPKDM1AEHMT2RCOR1SLC2A1 | |
| SCHEMBL8911900 | 0.88 | KDM1A (0.43) | KDM1AEHMT2RCOR1SLC2A1 | |
| SCHEMBL8890197 | 0.83 | PDE5A (0.48) | VCPRAD52SMARCA2 | |
| SCHEMBL8891551 | 0.83 | VCP (0.54) | VCP | |
| Hydrochloric Acid SCHEMBL8899106 | 0.82 | VCP (0.53) | VCP | |
| SCHEMBL8890872 | 0.80 | NPY5R (0.43) | VCP | |
| SCHEMBL8899767 | 0.79 | PRKCQ (0.42) | VCPKDM1AEHMT2RCOR1SLC2A1 | |
| SCHEMBL8889953 | 0.79 | KDM1A (0.47) | KDM1AEHMT2RCOR1SLC2A1RAD52 | |
| SCHEMBL8899135 | 0.78 | TRIM58 (0.53) | VCPKDM1AEHMT2RCOR1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |